In addition, P. bleo and P. grandifolia are the only exceptions of Pereskia which grow in areas receiving considerably high annual rainfall more than 187 mm per wet month. Antioxidant activity of different extracts from leaves of Pereskia bleo (Cactaceae) The leaves are thin, oblong to oblanceolate, glossy, and succulent, 6–21 cm long, and 2–7 cm wide . The ethyl acetate extract of P. bleo demonstrated the strongest antioxidant activity followed by the methanol extract reported by Sim et al. Murillo et al. Internet sources including MEDLINE (via Pubmed), Science direct, Scopus and Google scholar, and China Journals Full-Text Database (via CNKI) were searched for publications on this plant. It is usually taken raw or as a decoction of its fresh leaves. Fruits - the larger ones on the left are from the species Pereskia bleo Photograph by: I likE plants! ex Bercht. Pereskia species are divided into Clades A and B  (Table 1). The crude methanol extract and its ethyl acetate fraction had significant cytotoxic effects against human nasopharyngeal epidermoid carcinoma cell line (KB) . Pereskia bleo: A prickly source of antioxidants. The leaves are 4–11 cm long and 1.5–4 cm wide, simple, and deciduous in the dry season. Otero et al. Pharmacological evaluation of plants is based on their traditional uses. stream Hence, more research is warranted to further study its biological activities and chemical properties to understand its traditional usage and to develop novel therapeutics. β-Carotene-Linoleic Bleaching Assay. The snake venom neutralizing properties , antinociceptive effects , and toxicity [22, 31] of this plant have been evaluated through in vivo studies. Different solvent extracts of Pereskia bleo leaves were evaluated for total phenolic content (TPC) and antioxidant activities based on the Folin–Ciocalteu test and DPPH scavenging activities. 6 0 obj Therefore, further research needs to be carried out. Although they are different species, anatomical similarities in these two species support the evolution theory for cactus family . All of the mentioned bacteria are among the main causes of nosocomial infections and they have been developing antibiotic resistance [59–61]. Er et al. The flowers are white, cream, or pinkish with 2.5–5 cm diameter and strongly scented. We are committed to sharing findings related to COVID-19 as quickly as possible. Uses, Benefits, Cures, Side Effects, Nutrients in Parkinsonia Aculeata. Antibacterial and antifungal effect of the extracts, E. J. Edwards and M. J. Donoghue, “Pereskia and the origin of the cactus life-form,”, E. J. Edwards, R. Nyffeler, and M. J. Donoghue, “Basal cactus phylogeny: implications of, R. M. Ogburn and E. J. Edwards, “Anatomical variation in Cactaceae and relatives: trait lability and evolutionary innovation,”. Table 5 shows the weight percentage of the minerals reported by Abbdewahab et al. (Cactaceae) induces apoptosis in breast carcinoma, T47-D cell line. The resulted mass is moulded to oval shape objects which are dried in sun. Oxidation can lead to the production of unstable molecules called free radicals, which initiate chain reactions that can damage or even kill cells. This is followed by investigations of its antimicrobial and antiparasitic effects in vitro [8, 38, 41–43, 52]. On the other hand, P. bleo may contain some prodrugs which are metabolized to the active metabolites. "Both Pereskia bleo and Pereskia grandifolia have been used as natural remedies in cancer-related diseases, either eaten raw or taken as a concoction brewed from fresh plants. The leaves are the most commonly used part of P. bleo in traditional medicine. B. Abdul, M. M. E. Taha, and T. A. T. Ibrahim, “Energy-dispersive X-ray microanalysis of elements' content and antimicrobial properties of, S. Y. Liew, E. J. Stanbridge, K. Yusoff, and N. Shafee, “Hypoxia affects cellular responses to plant extracts,”, M. L. Tan, S. F. Sulaiman, N. Najimuddin, M. R. Samian, and T. S. T. Muhammad, “Methanolic extract of, K. Philip, S. N. A. Malek, W. Sani et al., “Antimicrobial activity of some medicinal plants from Malaysia,”, T. Rüegg, A. I. Calderón, E. F. Queiroz et al., “3-farnesyl-2-hydroxybenzoic acid is a new anti-Helicobacter pylori compound from, L. Rahalison, M. Hamburger, K. Hostettmann et al., “Screening for antifungal activity of Panamanian plants,”. A dry-deciduous, spiny shrub or small tree in the cactus family to about 8 m tall with oval, pale green leaves and very attractive and fairly large, red, rose-like flowers followed by edible but sour, round, yellow fruit The mineral content of the leaves was also investigated by using energy-dispersive X-ray microanalysis. It will also assist in setting appropriate policy and guidelines in the usage of herbal medicine. (P. bleo) are listed to be found in Singapore and Malaysia [7, 10, 11]. ���� Adobe d �� C Wahab, 2008 ) is a plant commonly used by the local communities in Malaysia due to its medicinal properties ( Er et al., 2007 ; Philip et al., 2009 ; Tan et al., 2005 ). USDA, “National Genetic Resources Program, Germplasm Resources Information Network—(GRIN),” [Online Database], 2012, K. S. Sim, A. M. Sri Nurestri, and A. W. Norhanom, “Phenolic content and antioxidant activity of crude and fractionated extracts of, E. Murillo, A. J. Meléndez-Martínez, and F. Portugal, “Screening of vegetables and fruits from Panama for rich sources of lutein and zeaxanthin,”. Pereskia bleo, a leafy cactus, is a medicinal plant native to West and South America and distributed in tropical and subtropical areas. In another study by Gupta et al. Table 7 shows the reported IC50 (μg/mL) values of these components in the different human cell lines. Among them, Pereskia aculeata Mill (P. aculeate), Pereskia grandifolia Haw (P. grandifolia), and Pereskia bleo (Kunth) DC. The total carotenoid content of the fruit was found to be 13.3 μg/g, making P. bleo fruit a high carotenoid food source among the wild fruits in Panama.  analyzed the fruit of P. bleo for lutein and zeaxanthin contents. Hassanbaglou et al. Singapore Npark Board, NParks Flora&Founa web, 2010, S. I.  reported high tumor inhibition activity in “potato disc inhibition assay” using crown gall tumors (LC50 77 ppm). 2,2-Diphenyl-1-picrylhydrazyl Hydrate (DPPH) Assay. In contrast, Pereskia species within Clade B typically delay forming bark, thus giving the stem the potential to become a major organ for photosynthesis . (1) Cytotoxic Components. However, in some studies, P. bleo did not show appreciable cytotoxic effect . A comprehensive review on Pereskia bleo has been presented. Figure 1 shows the photographs of different parts of P. bleo and P. grandifolia. The flowers are orange-red and grouped in 2–4 terminally and laterally. Traditional usage and methods of preparation of, Reported phytoconstituents in the leaves and fruits of, Percentage (% w/w) of mineral contents in the leaves of, A Review of Botanical Characteristics, Traditional Usage, Chemical Components, Pharmacological Activities, and Safety of, Department of Pharmacy, Faculty of Science, National University of Singapore, 18 Science Drive 4, Singapore, Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Evidence-Based Complementary and Alternative Medicine, https://florafaunaweb.nparks.gov.sg/Special-Pages/plant-detail.aspx?id=2324#, http://rmbr.nus.edu.sg/raffles_museum_pub/flora_of_singapore_tc.pdf, http://www.environment.gov.au/biodiversity/invasive/weeds/publications/guidelines/alert/pubs/p-aculeata.pdf, http://books.google.com.sg/books?id=YVwMM2OdO34C&q=Pereskia+bleo#v=snippet&q=Pereskia%20bleo&f=false, http://www.ars-grin.gov/cgi-bin/npgs/html/tax_search.pl?Pereskia+bleo%, http://www.ipni.org/ipni/plantNameByVersion.do?id=273592-2&version=1.3, http://mgonline.com/articles/exotics.aspx, http://plants.usda.gov/core/profile?symbol=PEGR14#, Chupa, Chupa melon, Najií, Najii De Culebra, Najú de esoubas, and Bleo de chupa (Spanish), Rose cactus, Bleo, Chinese rose, Spinach cactus, wax rose, and orange rose cactus (English), Making tea by boiling the leaves and/or the fruit and then drinking it warm or cool, Health maintenance and revitalizing the body, Making juice from the leaves and boiling in water and drinking every morning, Making decoction from the leaves and then using as a warm bath for muscle ache. << This spectrophotometric assay uses a stable radical 2,2′-diphenylpicrylhydrazyl (DPPH) as a reagent [8, 25]. Copyright © 2014 Sogand Zareisedehizadeh et al. Both are believed to have anti-cancer, anti-tumor, anti-rheumatic, anti-ulcer, and anti-inflammatory properties. A. Lim et al., “Inhibitory effects of various Ayurvedic and Panamanian medicinal plants on the infection of herpes simplex virus-1, I. Kola and J. Landis, “Can the pharmaceutical industry reduce attrition rates?”, H. Olson, G. Betton, D. Robinson et al., “Concordance of the toxicity of pharmaceuticals in humans and in animals,”.  evaluated the neutralizing effect of the ethanol extract of P. bleo on hemorrhagic activity of “Bothrops atrox venom” in mice. Hence, they have been more studied compared to the other plant parts. We will be providing unlimited waivers of publication charges for accepted research articles as well as case reports and case series related to COVID-19. The stems of the species of Pereskia within Clade A begin to form bark early in the life of the plant like most non-cacti. Seeds for sale starting at € 7.10. The antifungal activity of the water and methanol extract of P. bleo leaves against Cladosporium cucumerinum, a plant pathogenic fungus, has been reported , but they were not active against Candida albicans, a common human pathogen [42, 43]. Besides, in another study by Hattori et al. Pereskia bleo is known locally in Malaysia as pokok jarum tujuh bilah. Recent studies have reported the fruits from Pereskia aculeata Miller (AGOSTINI-COSTA et al., 2012) and the leaves from Pereskia grandifolia Haw (SIM et al., 2010) and Pereskia bleo (Kunth) DC. Hi! Look at this beauty first time it flowers am so happy makes winter feel like it's summer! The leaf of Pereskia bleo (Kunth) DC. Some of the cytotoxic components in P. bleo have been reported. Cacti are well-known desert plants and widely recognized by their specialized growth form of the stems and leaves. The scientific and common names of P. bleo are listed in Table 2. Review articles are excluded from this waiver policy. Pereskia bleo , a leafy cactus, is a medicinal plant native to West and South America and distributed in tropical and subtropical areas. DNA intercalation is another proposed mechanism of antiproliferative activity for P. bleo . $4�%�&'()*56789:CDEFGHIJSTUVWXYZcdefghijstuvwxyz�������������������������������������������������������������������������� ? R. P. Wunderlin and B. F. Hansen, “Atlas of Florida Vascular Plants,” 2008, N. P. Taylor, D. Zappi, P. Braun, and M. Machado, “. Cancer is one of the main causes of mortality and morbidity. Is talinum triangulare tumor inhibition activity in “ potato disc inhibition assay ” using crown gall tumors ( LC50 ppm. A month or two of constant persuasion, I ’ ve finally decided to this... Overview of the tested extracts sign up here as a food spice [ 1 11. Books and eBooks in the different human cell lines of TPTZ ( 2,4,6-tripyridyl-s-triazine ) tissues and cell lines and. 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